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194 startups and scale-ups in San Francisco are hiring AI and machine learning engineers right now, with 512 live roles between them, 120 of them opened in the last 30 days. Pick the ones you want and Haystack's AI agent fills in each employer's application for you.

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84% of candidates get an interview within 14 days568,056 candidatesRated 4.8/5 on G2
San Francisco · AI and ML engineersLive roles today
  • ANAnthropic logo
    AnthropicScale-up · 201-500 staff50 roles
  • DIDistyl logo
    DistylScale-up · Hybrid17 roles
  • SAScale AI logo
    Scale AIScale-up · 1,001-5,000 staff16 roles
  • CLClera logo
    CleraStartup · Office-first15 roles
  • CACapable logo
    CapableStartup · Office-first13 roles
  • PRPrimeintellect logo
    PrimeintellectStartup12 roles

and 188 more companies on the list

194 companies hiring now

Ranked by live roles (AI engineers, machine learning engineers and research scientists). Every company is a startup or scale-up; recruitment agencies are left out. Press Auto apply on any role and Haystack's AI agent fills in that employer's form for you.

The top 40 of 194 companies, most live roles first.

  1. ANAnthropic logo

    Anthropic

    Scale-up201-500 staffTechnology & Software

    50roles12 opened this month

    Anthropic is an AI research company dedicated to developing safe, reliable, and steerable AI systems for humanity's long-term well-being.

    Replied to 50% of the applications Haystack's agent sentAll 50 roles at Anthropic

  2. DIDistyl logo

    Distyl

    Scale-upHybrid

    17roles

    Distyl partners with enterprises to design and operationalise AI transformations, building AI-native businesses.

    All 17 roles at Distyl

  3. SAScale AI logo

    Scale AI

    Scale-up1,001-5,000 staffAI

    16roles1 opened this month

    To develop reliable AI systems for the world's most important decisions.

    Replied to 57% of the applications Haystack's agent sentAll 16 roles at Scale AI

  4. CLClera logo

    Clera

    StartupOffice-first

    15roles9 opened this month

    Clera is an AI-powered talent platform that connects candidates with startups by matching people with roles and arranging introductions to hiring teams.

    Replied to 60% of the applications Haystack's agent sentAll 15 roles at Clera

  5. CACapable logo

    Capable

    StartupOffice-first

    13roles

    Capable turns frontier intelligence into frontier medicines, aiming to improve human health by making data-driven decisions about talent and organisational design.

    All 13 roles at Capable

  6. PRPrimeintellect logo

    Primeintellect

    Startup

    12roles11 opened this month

    Primeintellect enables businesses to leverage AI and advanced analytics, providing an open superintelligence stack for training, deploying, and improving custom models.

    All 12 roles at Primeintellect

  7. LSLila Sciences logo

    Lila Sciences

    Startup

    9roles

    Lila Sciences builds scientific superintelligence with advanced AI and autonomous labs to accelerate discovery across various scientific domains.

    All 9 roles at Lila Sciences

  8. FAFaire logo

    Faire

    Scale-up1,001-5,000 staffRetail & Consumer Goods

    8roles2 opened this month

    Faire operates an online wholesale marketplace that connects independent retailers with brands, using technology to support small businesses and local communities.

    All 8 roles at Faire

  9. MEMercor logo

    Mercor

    Scale-up201-500 staffRemote-first

    8roles2 opened this month

    Mercor organises human intelligence to power the AI economy.

    All 8 roles at Mercor

  10. HU

    Hud

    Startup

    8roles1 opened this month

    HUD builds infrastructure for RL training data and evaluations for frontier AI agents, and operates a marketplace to sell these to frontier labs.

    All 8 roles at Hud

  11. PEPerplexity logo

    Perplexity

    Startup51-200 staffTechnology & Software

    8roles

    Perplexity aims to revolutionise how people access and understand information online using an AI-powered conversational search engine.

    All 8 roles at Perplexity

  12. BRBedrock Robotics logo

    Bedrock Robotics

    Scale-upRemote-first

    7roles1 opened this month

    Bedrock Robotics brings advanced autonomy to industrial applications, transforming everyday equipment into autonomous machines for logistics, manufacturing, and construction.

    All 7 roles at Bedrock Robotics

  13. MA

    Makermaker.ai

    StartupOffice-first

    7roles1 opened this month

    Makermaker.ai builds autonomous research agents for recursive self-improvement, using multi-agent systems to analyse machine learning experiments.

    All 7 roles at Makermaker.ai

  14. NSNiantic Spatial logo

    Niantic Spatial

    StartupHybrid

    6roles4 opened this month

    Niantic Spatial builds a living model of the world that people and machines can interact with, using real-world foundation models for physical AI.

    All 6 roles at Niantic Spatial

  15. WRWriter logo

    Writer

    Scale-upHybrid

    6roles3 opened this month

    Writer provides an AI writing platform that helps businesses scale content creation and improve brand consistency by transforming work.

    All 6 roles at Writer

  16. PHPhysicalintelligence logo

    Physicalintelligence

    Startup

    6roles2 opened this month

    Physical Intelligence aims to bring general-purpose AI into the physical world by developing learning algorithms to control any robot to do any task.

    All 6 roles at Physicalintelligence

  17. BABaseten logo

    Baseten

    StartupUnder 50 staffTechnology & Software

    6roles1 opened this month

    Baseten provides an inference cloud platform for developers to build and deploy high-performance machine learning applications and AI models.

    All 6 roles at Baseten

  18. AFAfterquery logo

    Afterquery

    Scale-upHybrid

    6roles

    Afterquery provides expert-curated data solutions and training for frontier AI models to enable machines to learn how experts think and make decisions.

    All 6 roles at Afterquery

  19. SCSciforium logo

    Sciforium

    StartupOffice-first

    5roles5 opened this month

    Sciforium builds AI serving infrastructure to enable any team to access the best AI capabilities across every modality without compromise.

    All 5 roles at Sciforium

  20. HAHandshake logo

    Handshake

    Scale-up501-1,000 staffTechnology & SoftwareRemote-first

    5roles2 opened this month

    Handshake aims to expand human opportunity by connecting students and recent alumni with employers, powering career discovery and upskilling in the AI economy.

    All 5 roles at Handshake

Every startup has its own application form.

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84%get an interview within 14 days

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sarah.okonkwo@myapplications.to
Reddit
Interview: Customer Success Manager
Now
Thu, Oct 30 · 2:00–2:45 PM · Google Meet
AcceptedMaybeDecline
Added to your calendar
Figma
Thanks for applying to Figma
Tue
Notion
We've received your application
Mon

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Which startups are hiring AI and machine learning engineers in San Francisco?

As of October 2026, 194 startups and scale-ups in San Francisco are hiring AI and machine learning engineers, with 512 live roles between them. The most are at Anthropic, Distyl, Scale AI, Clera, Capable. The full list on this page is rebuilt every day from the employers' own careers sites.

Which small companies (under 50 staff) are hiring AI and machine learning engineers in San Francisco?

Of the companies on this list, Baseten, Cognition, Mach9 have fewer than 50 staff on record. Use the "Under 50 staff" filter above the list to see only them. Team sizes come from company records and are not known for every company, so other small teams may be on the list too.

How is this list made?

Haystack reads the careers sites of more than 30,000 employers every day. This list takes the live roles in San Francisco for AI engineers, machine learning engineers and research scientists at companies recorded as startups or scale-ups, leaves out recruitment agencies, and ranks the companies by how many of those roles they have open.

Can I apply to all of these at once?

Not in one click, and you wouldn't want to. With Haystack Auto Apply you upload your resume once and pick the roles you want; Haystack's AI agent then fills in and submits each employer's own application form, asks you when a question needs your answer, and every reply lands in your Haystack inbox. Nothing is sent without your say-so.

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