Executive Director, Clinical Supply Chain

Hi,

Job Title: Executive Director, Clinical Supply Chain
Location: Bay Area, California, United States (On-site)
About the Client:
Our client is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. Their R&D pipeline includes multiple RAS(ON) inhibitor programs currently in clinical development.

The Opportunity:
The Executive Director, Clinical Supply Chain will provide strategic leadership and operational oversight for end-to-end clinical supply chain activities across the organization.

Key Responsibilities:

Strategic Leadership

• Define and execute the global clinical supply chain strategy aligned with the clinical development pipeline and long-term business goals
• Establish strategies/processes to ensure uninterrupted supply across all phases of development
• Serve as subject matter expert for clinical supply chain planning, risk management, and execution
• Build scalable processes and infrastructure to support early- through late-phase clinical programs
• Lead strategic planning on comparator sourcing management for timely, compliant, cost-effective product availability
• Manage clinical studies executed with collaboration partners
• Identify and implement clinical supply chain best practices

Clinical Supply Operations

• Oversee end-to-end clinical supply activities: demand forecasting, protocol reviews, packaging, labeling, distribution, returns
• Ensure uninterrupted supply of investigational medicinal products (IMP), including comparator products
• Champion monthly Development Operations planning (DnOP) process with PDM and Clinical Ops teams
• Ensure efficient global clinical supply chain distribution networks
• Oversee comparator products demand/supply planning with expert-level knowledge of comparator drugs and co-medication sourcing

Cross-Functional Collaboration

• Partner with Clinical Operations and Clinical Study Execution Teams (CSET)
• Collaborate with PDM, Quality, and Regulatory for compliant manufacturing, labeling, distribution
• Work with Finance on budgeting, forecasting, cost optimization

Compliance & Quality

• Ensure all clinical supply activities comply with GxP, ICH, FDA, EMA, and global regulatory requirements
• Lead inspection readiness activities for global filings

Team Leadership

• Build, lead, and mentor a high-performing clinical supply chain organization
• Establish performance metrics, development plans, succession planning
• Foster a culture of accountability and continuous improvement

Required Skills, Experience & Education:

• Bachelor''s degree (Supply Chain, Business, Engineering, or Life Sciences) with 20+ years of pharmaceutical supply chain experience; OR Master''s degree (MS/MBA) with 18+ years of experience
• CPIM/CSCP certification a plus
• 5+ years in a leadership/supervisory role
• Strong cGMP experience for small molecules; end-to-end supply/demand planning
• Effective vendor management skills
• Excellent cross-functional leadership and communication skills

Preferred Skills:

• Proven experience hiring, managing, and developing teams
• Experience with outsourced manufacturing operations (CMOs)
• Strong analytical and executive-level reporting skills
• Comfortable with ambiguity/complexity; self-starter