Operations & Project Management

Clinical Research IT Project Manager (VISA INDEPENDENT CANDIDATES ONLY)

SumasEdge CorporationRaleigh, NC🇺🇸United StatesPosted Oct 15, 2026

Quick Overview

Seniority

Mid Senior

Work mode

Hybrid

Location

Raleigh, NC, United States

Posted

17 hours ago

SAFeAgileJiraPMPStakeholder ManagementWaterfall

Job Description

Regulated environments such as CRO organizations experience is Huge plus

Job Purpose:

The Principal IT Project Manager is accountable for the end-to-end delivery of technology projects that are of critical importance and/or high complexity, ensuring predictable execution, strong governance, and measurable business outcomes. The role leads cross-functional delivery teams in a matrix environment, applying expert project management discipline to manage scope, schedule, budget, risks, dependencies, and stakeholder expectations. The Principal Project Manager operates with a high degree of autonomy, provides delivery assurance for key initiatives, and mentors other Project Managers through coaching, standards adoption, and escalation support.

Key Accountabilities:

Accountability	Supporting Activities
Delivery Leadership for Critical & Complex Technology Projects	Lead the full project lifecycle for critical and/or highly complex technology initiatives, ensuring delivery to agreed scope, timelines, budgets, and quality outcomes. Establish and maintain integrated delivery plans, milestone tracking, delivery governance cadence, and execution discipline across multi-team workstreams. Drive alignment across business and technology stakeholders to achieve outcomes, manage trade-offs, and resolve delivery blockers quickly and transparently. Ensure delivery artefacts, decisions, and approvals are documented and auditable in line with governance and delivery standards.
Stakeholder Management, Governance & Executive Communication	Act as the primary delivery point of contact for senior stakeholders, providing clear status, forecasting, decision points, and recommendations. Chair and run project governance forums (e.g., steering, working groups), ensuring risks, issues, scope changes, and dependencies are surfaced early and managed through to resolution. Manage stakeholder expectations through structured communications, change control, and transparent reporting, including executive-ready updates on progress, risk posture, and delivery impacts. Partner with Product, Engineering, Architecture, Security, and Operations to ensure solutions are feasible, supportable, and aligned to roadmaps and standards.
Delivery Assurance & Risk / Dependency Management	Proactively manage delivery risk by identifying, assessing, and mitigating risks, issues, and cross-project dependencies; implement recovery plans where required. Apply expert judgement to anticipate delivery failure modes (capacity, integration, vendor, compliance, operational readiness) and escalate with clear options and impacts. Support portfolio-level delivery by contributing to prioritisation discussions, dependency mapping, and capacity-aware planning for major initiatives.

Skills:

Expert knowledge of enterprise project management methodologies (Agile, Waterfall, hybrid) and governance practices, with strong delivery assurance capability.
Proven ability to lead delivery of large-scale, complex technology projects in matrixed, cross-functional environments.
Exceptional stakeholder management, communication, and influencing skills, including confident engagement with senior executives.
Strong risk, issue, dependency, and change control management, with a practical, outcomes-focused approach to decision-making and trade-offs.
High proficiency in project delivery and reporting tools (e.g., Azure DevOps, Jira, Smartsheet, MS Project, ServiceNow).
Strong commercial and financial acumen, including budgeting, forecasting, and benefits/value tracking for technology investments.
Able to operate with autonomy, resilience, and composure under pressure; adept at navigating ambiguity and organizational change.
Open and collaborative mindset, willingness to work as a team with integrity, honesty, and transparency.

Knowledge and Experience:

Demonstrated experience delivering complex, cross-functional technology programmes / projects at enterprise scale with multiple workstreams, vendors, and dependencies.
Strong understanding of digital, data, and technology ecosystems, ideally within life sciences, CRO, or regulated industries.
Experience working within governance models that require clear audit trails, decision logs, and structured change control.
Experience influencing without authority, aligning diverse stakeholder groups, and driving delivery through clear outcomes and disciplined execution.
Knowledge of GxP validation, or regulated technology environments are desirable.

Education:

Educated to degree level in Business, Technology, Engineering, Life Sciences, or an equivalent discipline.
Professional certifications desirable: PMP, PgMP, PfMP, SAFe, MSP, or similar.
Equivalent experience in enterprise project/portfolio management leadership also considered.