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Principal Scientist (PD/MSAT)

MytosLondon🇬🇧United Kingdom

Quick overview

SeniorityLeader
Employment typeFull Time
Work modeOn Site
LocationLondon, United Kingdom
RoboticsClinical TrialsComplianceContinuous ImprovementProcess ImprovementBusiness Development

Job description

About Us:

You rarely get the chance to change an entire industry. But that's the position we find ourselves in. Join us, and you’ll help scale cures to patients that need them sooner.

We’ve developed fully-automated cell manufacturing sites powered by custom robotics - to scale therapies to millions of patients. Last year, patients were cured of diseases like Parkinson’s Disease and vision loss using stem-cell derived cells - but today these Regenerative Medicines are produced by hand, meaning they’re too expensive and hard to scale. With our automated CDMO, these therapies can now be scaled globally at low cost.

We've announced partnerships across multiple therapies so far ranging from Parkinson’s, to hearing loss, to bone repair - and raised $24m to expand into the market faster, and accelerate our development! Within the next 12-18 months, neurons grown on our machines will be going into Parkinson’s patient brains.

We’ve assembled a world-class team to take on this challenge, with ex-Dyson engineers and Nature-published scientists working hand-in-hand. You can learn more about your potential Mytos teammates here: Team

Mytos is backed by Y Combinator, the most successful startup program in the world which produced companies such as AirBnb, Dropbox, and Ginkgo Bioworks.

The Role:

    We are looking for a high-growth principal PD/MSAT Scientist to join our Biology team and push the limits of automation in cell therapy manufacture. This is a unique opportunity to learn how to execute projects at the interface of engineering and biology with a direct impact to patients.

Core Responsibilities:

  • Provide technical leadership in the set up and operation of Mytos Bio’s CDMO site in Stevenage. Travel between London and Stevenage sites will be required where necessary.
  • Lead process development and analytical method development projects in line with customer requirements.
  • Plan and execute technology transfer activities, ensuring compliance with relevant regulatory standards.
  • Drive continuous process improvement through the implementation of best practices, methods, and high quality standards.
  • Support resource planning and timeline development for new projects.
  • Help build out the teams technical capabilities by supporting hiring efforts and mentoring colleagues.
  • Support business development activities through direct client engagement and involvement in the drafting of sales proposals.

Skills & Experience

    Required:

  • PhD in Cell Biology (or related discipline) with 3+ years of industry experience, or 5+ years of relevant industry experience.
  • Subject matter expertise in cell therapy development and manufacture across the PD → MSAT → cGMP pipeline.
  • Subject matter expertise in optimising human stem cell culture (ESC/iPSC), differentiation, and characterisation under cGMP conditions.
  • Strong understanding of regulatory requirements for cell therapy manufacture (MHRA, EMA, or FDA).
  • Experience authoring quality documentation for cGMP manufacturing and QC.
  • Demonstrated ability to lead, manage and deliver complex projects with multiple dependencies.
  • Strong experimental design and analytical skills.
  • Excellent communication and teamwork skills across multiple levels (customers, team members and inter departmental).
  • Experience in a line manager capacity.

    • Desired:

  • Prior experience developing cell therapy products that have been taken to Phase I clinical trials or beyond.
  • Prior experience working in or with CDMOs.

Salary and Benefits

  • Competitive salary with stock options
  • Lunch covered daily
  • Collaborative team environment with very high potential to learn new skills
  • 24 days holiday (excluding bank holidays)
  • Pension
  • Awesome colleagues and an office in the Imperial College Innovation hub in White City, where you’ll be based.
We’re building a team that enjoys moving fast, strives for continuous improvement through learning from mistakes and is passionate about work that contributes to solving real world problems. Join us if you want a fast-paced environment, where you’re empowered to make decisions and do the best work of your career.

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