Senior Director, Global Forecasting

The Opportunity:

Reporting directly to the Executive Director, Global Forecasting, the Senior Director, Global Forecasting role requires strategic thinking and expertise to provide critical contributions to disease area strategy, life-cycle planning and product and portfolio decisions. The Senior Director, Global Forecasting will act a strategic thought partner cross-functionally. They will develop, refine, and communicate key strategic and revenue forecast assumptions and analyses to inform and support portfolio investment and lifecycle strategy decisions across the organization. This role will work directly with other Global and Regional Forecasting leads to ensure consistency in forecast approach, assumptions, and analyses. The ideal candidate will have experience working on pipeline molecules in Oncology, strong problem-solving skills, a strategic mindset, and will exhibit curiosity, flexibility, and be comfortable with ambiguity. The role will address increasingly complex interactions among products and indications within and across tumor types, translating forecast scenarios into actionable insights for long-range planning, supply planning, and go/no-go decisions.

This position would ideally be based at our headquarters in Redwood City, CA., however open to remote candidates who are willing to travel to our CA office on a regular basis.

Responsibilities include:

• Leading a team of forecasters responsible for developing and maintaining global forecast models for a given tumor type and integrating these forecasts to assess interactions across products, indications, and the broader portfolio. Specific activities include:

• Ensuring alignment to Global forecasting standards and governance processes; partnering with global and regional forecasting leads to establish and maintain a shared framework for methodologies, core assumptions, scenario definitions, and forecast review, with consistency where relevant and flexibility for justified market differences.

• Developing and maintaining patient-based forecasts and complex scenarios within indications and across the portfolio as multiple products and indications enter the same tumor type. Assessing treatment sequencing, overlapping eligible populations, combinations, launch timing, and substitution or complementary use to quantify incremental portfolio opportunity and avoid double counting patients and demand.

• Communicating and aligning key internal stakeholders around key forecast assumptions.

• Understanding complex markets, disease states, competitive landscapes, and relevant market and managed care dynamics and using this knowledge to develop strategic forecasts and plans.

• Synthesizing and communicating the similarities, differences, and considerations necessary to inform Global clinical development plans.

• Conducting rigorous opportunity assessments, sensitivity analyses, and risk quantification to clarify key uncertainties, interdependencies, and decision thresholds for portfolio prioritization, investment, and go/no-go decisions. Partnering with the Portfolio Strategy team to develop processes and systems.

• Partnering across the forecasting team and with Finance, Supply Chain, and cross-functional teams to translate patient, treatment duration, and utilization assumptions into revenue and demand scenarios for long-range plans, budgets, supply and capacity planning, and launch readiness; communicating forecast ranges, risks, and changes to inform timely decisions.

• Partnering closely with other Insights and Analytics functions (Disease Area Insights, Data Analytics) to inform the forecast.

• Working closely with Global Commercial Development, Clinical Development, Portfolio Strategy, Finance, and Medical Affairs to support early-stage decision making.

• Working closely with the Regions to ensure consistency; develops and communicates understanding of differences in forecasts. Documenting and reconciling material differences in assumptions, methods, and outputs, with clear rationale reflecting local evidence and market conditions, and ensuring their implications are understood in global and regional planning.

• Providing forecasting expertise, tools, and hands-on analytical support to regional and local teams as needed, adapting support to local capabilities and priorities. Helping teams apply the shared framework to local forecasting needs, build capabilities, and share insights and effective practices across markets.

• Maintaining an in-depth understanding of Revolution Medicines’ diverse product offerings, competitive positioning, and the broader market dynamics shaping the industry's future.

• Collaborating with vendor partners to manage various deliverables and analyses.

• Travel domestically and internationally as needed, typically up to 25–30%.

Required Skills, Experience and Education:

• Bachelor's degree required (MBA preferred) with 12+ years of progressive experience in a pharmaceutical, biotechnology, or strategic consulting role with 8+ years of experience in a related forecasting role.

• Experience developing long-range patient-based oncology forecasts and complex scenarios that capture interactions among multiple products and indications within the same tumor type and across a portfolio.

• Experience translating forecast uncertainty and portfolio scenarios into insights supporting long-range planning, supply planning, investment prioritization, and go/no-go decisions.

• Experience developing and supporting early-stage forecasting efforts; comfortable with ambiguity and uncertainty and rapidly evolving information and priorities.

• Experience working with global, regional, and local teams to establish shared forecasting approaches, explain material differences, and provide practical analytical support tailored to local needs and capabilities.

• Track record of being a collaborative team player, and adaptive to meet the needs of a growing business.

• Strong problem solver with experience leveraging a variety of research and analytical vendors, study designs, and building quality research vendor partnerships.

• Demonstrated ability to influence senior management and key business partners.

• Proven experience in a smaller, rapidly growing, company.

• Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines.

• Ability to represent Revolution Medicines well: strong interpersonal skills including verbal and written communication.

• Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients.

Preferred Skills:

• 8+ years of experience in patient-based forecasting with focus in Oncology.

• Experience with targeted Oncolytics.

• Experience managing teams.

• Demonstrated ability to synthesize complex information and influence decision-making at the executive level.

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