Senior Manager, People Experience

Overview

We are seeking a People Experience Partner to join our newly established People Experience team that will deliver a best-in-class employee and leader experience across the organization. This role will be responsible for partnering with Alnylam managers across Expertise Areas (EAs) to strengthen leadership capability, elevate performance, and foster a culture of collaboration, inclusion, integrity, and accountability. As a People Experience Partner, you will serve as a trusted advisor, enabling leaders to grow talent, navigate complex employee situations, and uphold Alnylam’s commitment to its people and values.

This role will focus on providing managers with coaching and guidance on their own leadership capabilities as well as matters regarding employee performance and development. People Experience Partners will also work with managers and employees in cases of discipline and Employee Relations matters, and will support employee offboarding, when needed. This role will also provide important support to Alnylam’s performance and compensation cycle.

This position is hybrid and will be primarily located in Cambridge, MA.

Responsibilities

• Serve as a trusted People Experience Partner to leaders across Expertise Areas, coaching managers to strengthen leadership capability, team effectiveness, and performance in alignment with company values and culture.
• Advise and coach managers on performance issues, including development plans and Performance Improvement Plans (PIPs), ensuring timely, fair, and well‑documented outcomes.
• Own end‑to‑end case management for assigned matters, including documentation, escalation, and resolution, leveraging ServiceNow to ensure accurate and consistent people processes.
• Lead employee relations and disciplinary matters with discretion, empathy, and rigor, ensuring consistent application of policies, employment law, and best practices.
• Partner closely with Employee Relations, Legal, HR Business Partners, and HR Capability teams on investigations, involuntary separations, reductions in force, and other high‑risk or sensitive situations.
• Provide guidance on absence management, leaves of absence, and workplace accommodations, collaborating with specialized teams where needed.
• Identify trends, root causes, and insights across cases, proactively recommending actions to strengthen culture, leadership effectiveness, and the employee experience.
• Support enterprise performance and compensation cycles by coaching managers and reinforcing consistent, high‑quality execution.

Qualifications

• 5-10 years Human Resources experience required.
• Experience with HR Generalist work, Employee Relations and Performance Management preferred.
• Strong working knowledge of employment law and HR best practices.
• Proven ability to manage complex employee situations with discretion and neutrality.
• Exceptional communication and influencing skills, with experience providing manager coaching and development.
• Demonstrated high emotional intelligence and sound judgement with the ability to make decisions with empathy as well as discipline to ensure consistency.
• Able to operate in a disciplined environment with an eye to data integrity and high quality case management.
• Able to leverage case management systems (ServiceNow a plus) and analyze data trends for ongoing continuous improvement.

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Before applying, please review Alnylam's ⁠Candidate Privacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment.

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