Haystack
← Back to Jobs
Technology
TB

Sr Systems Engineer

Twist BioscienceUSA - Portland🇺🇸United StatesPosted Aug 27, 2026

Why This Role Stands Out

You'll thrive as a Sr. Systems Engineer at Twist Bioscience, leading the development of innovative automated lab instrumentation and bioprocess technologies at the exciting intersection of hardware, software, and biology. This role offers a fantastic opportunity to enhance your skills in automation, scripting, and cross-functional collaboration within a company dedicated to operational excellence and product quality.

Quick Overview

Seniority
Mid Senior
Work mode
Hybrid
Location
USA - Portland, United States
Posted
4 weeks ago
C#PythonScheduling

Job Description

Sr. Systems Engineer (Onsite in Wilsonville, OR)

Summary

We are seeking a Senior Systems Engineer to join our team in Portland, OR (PDX). In this role, you will lead the development, validation, and integration of cutting-edge automated laboratory instrumentation and bioprocess technologies. Working at the intersection of hardware, software, and biology, you will design automated workflows, write custom integration scripts, and connect robotic systems with enterprise LIMS infrastructure to drive operational excellence and product quality under ISO 13485 standards.

What You’ll Do

  • Develop, validate, and release new processes and technologies to achieve cost-effectiveness and improved product quality
  • Develop and test protocols, scripts, and systems to automate certain bioprocesses
  • Operation and maintenance of a range of scientific instruments and tools with a focus on laboratory automation systems and cross-integration systems
  • Collaborate with multi-disciplinary teams in troubleshooting and resolving issues concerning equipment and systems
  • Prepare and participate in documentation, knowledge transfer, and training activities
  • Follow regulatory and ISO 13485 requirements

What You’ll Bring

  • Ph.D. or MS with 3 years, BS with 5 years of related experience in Biomedical Engineering, Chemical Engineering, Mechanical/Electrical Engineering, or related field
  • Experience in developing automated instrumentation for bioprocesses
  • Experience with DoE for testing and troubleshooting of certain processes 
  • Experience in designing and writing scripts (C#, Python, etc) using control software or dynamic scheduling software native to laboratory automation systems and cross-integration systems
  • Experience with sample tracking software and developed interfaces between robotic instrumentation and LIMS systems (MES/Maestro, Twist build) 
  • Excellent scientific computation and data analysis capabilities
  • Hands-on skills to assemble and maintain hardware
  • Experience with biological instrumentation for liquid transfer, PCR, cell-based cloning, DNA extraction, and purification is desirable
  • Working collaboratively with other functional groups
  • Excellent communication and writing skills, and ability to work in a fast-paced team environment 

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

Similar jobs