Quick overview
Job description
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Associate Manufacturing Scientist I (third shift) supports the production of drug substances and drug products. Their responsibility will focus on the preparation of solutions and reagents by following standard protocols. This technically focused second shift position supports lab work, helps solve problems, and effectively communicates with colleagues.
3rd shift work hours are 10 pm – 8:30 am and includes a 15% shift differential.
Responsibilities
- Follow batch records, SOPs, and work instructions to detail
- Document all operations in batch records and notebooks
- Comply with GMP protocols
- Assist other chemists within the CMC group during synthesis and chromatography of oligonucleotides including:
- Reagent solution preparation
- Column Packing
- Mobile phase preparation
- Fraction collection
- Operate TFF to desalt purified RNA solutions
- Operate a lyophilizer and package solid drug substance
- Execute processes as part of a team to ensure production timelines are kept and quality product is produced
- Maintain a clean work space
- Maintain safety by wearing required personal protective equipment
Requirements
- BS or MS in chemistry, biochemistry, engineering, or related scientific field
- Entry level to 3 years experience in a similar position
- Good verbal and written communication skills
- Ability to work in a team environment
- Ability to pay attention to detail
Preferred
- Experience working in a GMP setting with controlled documentation
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
Similar jobs
- AB

Product Application ScientistRecently posted Auto Apply
Alamar Biosciences · Fremont · Hybrid 🇺🇸
Inventory ManagementTechnical SupportSalary not listed - AB

Field Application Scientist - SouthwestRecently posted Auto Apply
Alamar Biosciences · San Diego · Hybrid 🇺🇸
CRMERPMarketing Automation+2Salary not listed - HA

Research Engineer / Scientist, Reinforcement LearningRecently posted Auto Apply
Harvey · Remote · Remote 🇺🇸
PythonEngineering$230k - $450k/yr - WA

2027 Summer Intern, PhD, Research Scientist InternRecently posted Auto Apply
Waymo · Mountain View · Hybrid 🇺🇸
RoboticsDeep LearningAutonomous Driving+2Salary not listed - FI

Member of Technical Staff, Research (2026 PhD New Grad) - SeattleRecently posted Auto Apply
Fireworks · Greater Seattle Area · Hybrid 🇺🇸
Deep LearningC++PyTorch+4Salary not listed - TR
Multi-scale Physics Battery Modeling InternRecently posted Auto Apply
Tri · Los Altos · Hybrid 🇺🇸
RoboticsPythonData AnalysisSalary not listed - TR
Accelerated Science Intern, Representation Learning for Molecules and MaterialsRecently posted Auto Apply
Tri · Los Altos · Hybrid 🇺🇸
LinearRoboticsPyTorch+2Salary not listed - RE
Scientist, Microglia Therapeutics TeamRecently posted Auto Apply
Retro · Redwood City · On-site 🇺🇸
Healthcare$150k - $190k/yr - TT
Member of Technical Staff, Research EngineeringRecently posted Auto Apply
True Talent Solutions Partners · Mountain View · On-site 🇺🇸
LLMPyTorchPython+1EngineeringSalary not listed - TT
Member of Technical Staff, Applied ResearcherRecently posted Auto Apply
True Talent Solutions Partners · New York · On-site 🇺🇸
FastAPIConcretePyTorch+2Salary not listed - AT

Associate Director, Pharmacokinetics & PharmacodynamicsRecently posted Auto Apply
Atrium Therapeutics · San Diego · Remote 🇺🇸
GCPHealthcare$185k - $205k/yr - AB

Senior Scientist, Machine Learning ResearchRecently posted Auto Apply
A-Alpha Bio · Seattle · Hybrid 🇺🇸
AWSDeep LearningPyTorch+1TechnologySalary not listed
