Integration Engineer - SAP, EWM & Shop-floor Systems (L2/L3)

12 of the top 15 pharma generic companies in the world trust Leucine to manufacture the drugs that reach millions of patients every day.
Pharma manufacturing is one of the last large industries still running on paper, Excel, and tribal knowledge. A single missed step in a batch record can mean a recall, a regulatory warning, or a drug that should never have left the plant.
Leucine is the AI platform replacing all of it. Series A, backed by top-tier global investors, 60+ pharma enterprises in production, and the team that's going to define this category.
About the Role:

We are looking for an Integration Engineer to join our platform team and own the integration layer between Leucine applications and the systems around them on a pharma shop floor — SAP ERP and SAP EWM at the enterprise and warehouse level, weighing balances, floor scales and label printers at the point of work, and PLCs, SCADA, historians, LIMS and QMS across the L2/L3 layer.
You will work directly on customer-facing integration projects — understanding customer data schemas, configuring and testing integrations with our applications, and building and maintaining our Reify (edge/IoT) and SAP integration pipelines.
This is a hands-on role on production systems used by real pharmaceutical manufacturers, with direct exposure to customer SAP, automation, IT/OT and QA teams.
Key Responsibilities:
SAP & ERP Integration (L4 ↔ L3)

• Design, configure and support integrations between Leucine MES and SAP (S/4HANA / ECC) — process order download, BOM/recipe and material master sync, goods issue/receipt order confirmations, batch characteristics, and QM inspection lots / usage decisions
• Build interfaces over REST/OData, IDoc, BAPI/RFC and middleware (SAP PI/PO, CPI/BTP), with idempotency, retries, error queues and reconciliation
• Monitor SAP interfaces, investigate data-flow issues and drive configuration changes to resolution

• Configure ontology Action-Effects so MES events (e.g., batch rejected, material dispensed) trigger the correct outbound postings to SAP.
  Warehouse Management (SAP EWM / WMS)
• Integrate staging to production supply areas, dispensing requests, warehouse tasks, handling units and return-to-stock flows.
• Enforce material status (quarantine / released / expired) and FEFO at point of use, and keep ERP–EWM–MES inventory reconciled
  Weighing Balances, Scales & Printers.
• Integrate analytical/precision balances and floor scales (e.g., Mettler Toledo, Sartorius) via MT-SICS, serial/TCP-IP, OPC UA or vendor middleware — automatic weight capture, tare/gross/net logic, tolerance checks and calibration-status interlocks
• Integrate industrial label printers (e.g., Zebra, Honeywell, SATO) and barcode / 2D DataMatrix / RFID scanners; build dynamic label templates (ZPL, BarTender, NiceLabel/Loftware) with reprint governance.
  L2 & L3 Systems / Reify Edge Platform
• Build, maintain and troubleshoot Reify (edge platform) integrations — device connectivity, data extraction and transformation logic, and scaling of edge services.
• Connect Leucine applications to PLC/SCADA/DCS, process equipment and historians (OPC UA, Modbus, MQTT, AVEVA PI) to capture CPPs, equipment states, alarms and runtime counters.
• Integrate with LIMS, QMS, DMS and EMS so quality and environmental data flow into the electronic batch record, aligned with ISA-95 / ISA-88.
• Connect Leucine applications to PLC/SCADA/DCS, process equipment and historians (OPC UA, Modbus, MQTT, AVEVA PI) to capture CPPs, equipment states, alarms and runtime counters.
• Integrate with LIMS, QMS, DMS and EMS so quality and environmental data flow into the electronic batch record, aligned with ISA-95 / ISA-88.
  Data, Scripting & Testing
• Analyze and document customer database schemas and data models, and map them to Leucine application data structures
• Write and debug JavaScript-based transformation/extraction scripts used in integration pipelines
• Write SQL queries (PostgreSQL) for data validation, reconciliation and troubleshooting
  Validation & Delivery
• Author interface specifications, data mappings, error-handling matrices, runbooks and customer-specific configuration documentation
• Support SIT, IQ/OQ/PQ and CSV under GAMP 5 / CSA, ensuring interfaces meet 21 CFR Part 11, EU Annex 11 and ALCOA+
• Own hypercare after go-live and collaborate with the engineering team and customer technical teams

• JavaScript (primary) - solid fundamentals: data structures, async patterns, JSON manipulation, and clean transformation/scripting logic.
• SQL (PostgreSQL) - joins, aggregations and analytical queries; understanding of schemas, keys and constraints
• SAP Integration - hands-on with PP-PI, MM, QM, WM/EWM via IDoc, BAPI/RFC, OData or middleware
• REST APIs & data formats - REST/SOAP, JSON, XML, CSV
• Shop-floor integration - Balances/Scales and Label printers; working knowledge of OPC UA, Modbus or MQTT and PLC/SCADA concepts
• Edge services - Maintaining and scaling edge/IoT services
• GxP awareness - Data integrity, 21 CFR Part 11 and CSV; you understand why an interface failure can be a GMP deviation
• Strong analytical and debugging mindset - Comfortable digging into unfamiliar data to figure out how it is structured

• Good written communication for documenting schemas, interfaces and configurations
  Nice to Have:
  
• Exposure to Java Spring Boot
• Familiarity with Linux command line, Docker and Git
• Awareness of message queues / event streaming (e.g., Kafka) or ETL/data pipeline concepts
• Experience with another MES (e.g., Werum PAS-X, Opcenter, PharmaSuite, Syncade, Körber)
• SAP certification (EWM, PP-PI, QM or Integration Suite)
• Exposure to serialization (DSCSA / EU FMD), LIMS (LabWare, LabVantage) or QMS (TrackWise, Veeva)
• Familiarity with Kepware, Ignition, Postman/Newman and OT cybersecurity (ISA/IEC 62443)
  Who Should Apply:
  
• Engineers with a B.E./B.Tech/M.Tech in Computer Science, IT, Instrumentation, Electronics or a related field
  

• Be part of a fast-growing SaaS company transforming the future of pharmaceutical manufacturing through cutting-edge technology
• Collaborate with a passionate, high-performing team building innovative AI-powered digital solutions
• Take ownership of impactful client implementations from day one, with ample opportunities for learning, career growth, and professional development
• Enjoy a competitive compensation package designed to reward your contributions
• Comprehensive Health Insurance with industry-leading coverage for your peace of mind
• Complimentary Meals & Refreshments: Stay energized with unlimited breakfast, lunch, snacks, and dinner provided at the office
• Family-Friendly Leave Policies, including Paternity Leave and Compassionate Leave, to support you through life's important moments