Quick Overview
Job Description
Immediate need for a talented Scientist - III (Senior). This is a 06+months contract opportunity with long-term potential and is located in South San Francisco, CA(Onsite). Please review the job description below and contact me ASAP if you are interested.
Job ID: 26-31075
Pay Range: $70.23 - $76.97/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).
Key Responsibilities:
- Design, execute, troubleshoot, and interpret molecular interaction studies that support hit identification, lead optimization, and candidate selection.
- Generate and analyze binding affinity, kinetics, avidity, epitope binning, competition, and developability data for antibodies, bispecifics, and other biologic modalities.
- Coordinate with project scientists to define assay plans, prioritize samples, and deliver results according to program timelines.
- Document methods, results, and conclusions accurately in electronic systems, reports, and presentation-ready summaries.
- Communicate data, technical risks, and recommended next steps clearly to project teams and stakeholders.
- Operate interaction analysis platforms such as SPR, high throughput SPR using Carterra, BLI, and related technologies.
- Optimize established assay formats and workflows to improve throughput, robustness, data quality, and turnaround time.
- Identify assay or instrument issues, perform routine troubleshooting, and partner with internal platform owners as needed.
- Apply rigorous experimental design, appropriate controls, and quantitative data interpretation to address project questions.
Key Requirements and Technology Experience:
- Master's degree with minimum 5 years of hands-on experience or PhD (preferred) with minimum 3 years of hands-on experience in biophysics, biochemistry, chemistry, molecular biology, protein sciences, biomedical engineering, or a related field.
- Strong foundation in biomolecular interactions and protein characterization.
- Hands-on molecular/protein/antibody interaction experience with SPR/BLI/Biacore/Carterra and binding kinetics/affinity analysis.
- Demonstrated ability to troubleshoot experiments, interpret complex data, and deliver high-quality results within defined timelines.
- Excellent written and verbal communication skills, with the ability to work effectively in a collaborative, multidisciplinary environment.
- Experience supporting therapeutic antibody, multispecific, or other biologics discovery programs in an industry setting.
- Experience with epitope binning, competition assays, cell binding characterization, receptor pharmacology, or developability assessment.
- Knowledge of antibody engineering, Fc biology, and relationships between protein structure and function.
- Familiarity with laboratory automation, high throughput screening workflows, and data analytics.
- Programming or data science experience using Python, R, Spotfire, or similar tools.
Our client is a leading Pharmaceutical Industry, and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.
Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
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