Computational Scientist

Software Guidance & Assistance, Inc., (SGA), is searching for a Computational Scientist for a contract assignment with one of our premier Pharmaceutical clients in South San Francisco, CA .
Responsibilities :

• Multimodal perturbation datasets are becoming increasingly large and available, and understanding which data contribute most to model performance is an increasingly important question. The firm's lab has generated a large multimodal perturbation dataset. The contractor will train and evaluate models on this data to characterize how different portions of the dataset contribute to model learning, and will evaluate model performance and model outputs against experimental data.
• Ownership of a clearly scoped, business-critical workstream with defined deliverables.
• Direct collaboration with the project lead and access to an established, documented analysis codebase and cluster compute.
• Work with some of the most talented people in the biotechnology industry.

Required Skills :

• PhD in a computational discipline, or equivalent research experience
• Training and evaluating deep learning models in PyTorch, including designing and executing controlled train/test split experiments on a SLURM cluster.
• Strong applied statistics
• Proficient scientific Python (numpy, pandas, scanpy/anndata) and reproducible, documented analysis practice.

Preferred Skills :

• Preferred majors: Computational Biology, Computational Sciences, Statistics or Machine Learning
• Experience with single-cell transcriptomics
• Experience with analysis of CRISPR perturbation screens (perturb-seq or similar).
• Familiarity with representation learning
• Familiarity with image analysis

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SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at .
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