Senior Clinical Research Associate

Freelance/Self-Employed Contract | Remote-based with 8 to 10 days onsite per month

We are partnering with a mid-size, fast-growing CRO to find an experienced Senior Clinical Research Associate based in the UK for a freelance contract. This is a great opportunity for a seasoned CRA who wants the autonomy of freelance work combined with the stability of a well-established, growing organisation.

The Role

You'll manage a portfolio of sites, balancing remote monitoring with regular in-person visits (approximately 8 to 10 days onsite per month). You'll take ownership of the full monitoring lifecycle, from site qualification through to close-out, while acting as a trusted point of contact for investigators and site staff.

Key Responsibilities

• Conduct qualification, initiation, interim monitoring, and close-out visits across assigned sites
• Perform source document verification, CRF review, and query resolution across paper and EDC systems
• Ensure ongoing site compliance with ICH-GCP, the UK Medicines for Human Use (Clinical Trials) Regulations 2004 (as amended), and MHRA reporting requirements
• Identify site-level risks proactively and work with sites to resolve issues before they escalate
• Review subject safety data and informed consent documentation
• Maintain accurate, timely documentation and TMF filings
• Oversee IP accountability, storage, and reconciliation at site level
• Build and maintain strong relationships with investigators, site teams, and sponsor contacts
• Balance a mixed remote/onsite model efficiently, managing your own schedule and travel

About You

• Based in the UK
• 5+ years' CRA experience, with a strong monitoring track record across multiple sites
• Confident working independently as a freelancer, with strong self-organisation and time management
• Comfortable with a hybrid remote/onsite rhythm and regular travel
• Experience with CTMS and EDC platforms
• Life sciences, nursing, or related degree/qualification

If you're a self-driven Senior CRA based in the UK, looking for a freelance opportunity with real autonomy, we'd love to hear from you.