Why This Role Stands Out
This hybrid Lead Platform Engineer role offers a fantastic opportunity to architect and lead critical infrastructure for cutting-edge AI and sequencing operations, with significant impact on a rapidly scaling startup. You'll thrive here if you have a strong background in building reliable distributed systems and enjoy technical leadership, with the flexibility to work from South San Francisco. Don't miss out on this chance to shape the future of biotech innovation!
Quick Overview
Job Description
Job Title: LEAD PLATFORM ENGINEER
Work Location: South San Francisco, CA
Duration : Full Time
- Technical lead for the compute, data, AI, and security infrastructure that runs our sequencing operation.
- You will own core services that orchestrate lab devices (robots, sequencers, on-prem Linux servers) and the data ingestion pipeline
- Build cloud infrastructure and data pipelines to house, process, and deliver terabytes of sequencing data
- Design infrastructure to orchestrate millions of bioinformatics tasks (queues, workflow orchestration, scheduling)
- Build AI infrastructure and internal tooling to enable agentic systems:
- Quality Scientist Agents - monitor operations end-to-end, surface anomalies, and intervene/escalate when quality or reliability issues appear
- Logistics Agents - coordinate drivers around the world to move packages to labs and carriers
- Bioinformatics Coding Agents - long-running agents for adaptive analysis of diverse sample types with unknown/shifting data distributions
- This opportunity aligns with your focus on backend and infrastructure roles in San Francisco within the AI industry.
WORK EXPERIENCE:
- 6+ years of experience in platform/backend/infrastructure engineering.
- Must have impactful experience at a startup while it has scaled (ideally Seed - Series C).
- Can design + build reliable distributed systems (queues, orchestration, state machines) and ship them to production.
- Led projects and mentored engineers on small teams.
- Former successful founder or founding engineer.
Education
- BS in CS, Engineering, Math, Physics or equivalent technical degree
Skills:
- Strong AWS orchestration (ECS, Batch, StepFunctions) + Python backend work (FastAPI/Django)
- Linux server administration and distributed task queues (Celery/SQS)
- Experience building LLM/agent systems (tooling, evaluation, safety/permissions, prompt + workflow design)
Soft skills
Very hungry and wanting to take a step up in their career. Senior/Staff -> Lead engineer
Miscellaneous
Up to date with newest AI tooling
Genuine curiosity about biotech/science domains
Traits to avoid
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