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Staff Full Stack/Back End Engineer (NodeJS+React)

Deep OriginSouth San Francisco, California🇺🇸United StatesPosted 24 Jun 2026

Why This Role Stands Out

As a Staff Full Stack/Back End Engineer at Deep Origin, you will architect and build critical features for a groundbreaking operating system for science, directly impacting the future of life sciences. This role is ideal for experienced engineers with a passion for complex system design and scaling, offering significant ownership and the chance to contribute to a mission-driven company founded by an Oculus co-founder. Embrace this opportunity to drive innovation and apply your expertise in a high-impact environment.

Quick Overview

Work Type
On Site

Job Description

About Deep Origin

Led by Michael Antonov, a co-founder of Oculus, and well-funded by Formic Ventures, Deep Origin is poised to reinvent the way scientists work and life science innovations come to life. We see a future largely free of diseases, with a 150-year lifespan being the norm. To get there, we are building an operating system for science, enabling scientists to be more productive and to bring tomorrow's ideas to life quickly and at a reasonable cost.

Role Description

We are seeking a talented and experienced Staff Engineer to join our dynamic team. You will be a key member of the software engineering team, building our key functionality and integrating with key partners. You will have ownership in key software feature areas and their architectural design, as well as software implementation with a high level of independence and impact. You will work closely with cross-functional teams to create robust, user-friendly applications that drive the efficiency and effectiveness of biologists and researchers in their scientific endeavors.

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

  • 10+ years of experience designing, building, and operating complex, highly scalable, distributed applications and systems
  • 5+ years of hands-on software development experience with React/TypeScript/JavaScript/NodeJS
  • Experience with both relational databases (e.g., Postgres) and NOSQL (e.g., MongoDB)
  • Knowledge of Kubernetes and Cloud infrastructure/deployment tools (specifically with cluster operations and operators)
  • Has built platforms from an early stage
  • Has scaled platforms to handle many users (10,000+ DAU)
  • Has extensive system-design experience
  • Has experience designing systems with complex datasets/relations
  • Has experience working with distributed systems/platforms
  • Thinks about architecture first and how the code fits in second
  • Has experience working with/implementing a multi-tenant system
  • Systematic problem-solving approach, coupled with a strong sense of ownership and drive
  • Ability to work both independently and on a team
  • Experience working in high-energy startups with fast product delivery mechanisms
  • Must work onsite at least 3 days a week.
  • Opportunity to collaborate with highly talented teams
  • Competitive compensation package with meaningful equity
  • Comprehensive health, dental, and vision coverage
  • Annual team gatherings and company events.

Skills

MongoDB
JavaScript
Kubernetes
React
TypeScript

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