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AI Research Scientist - Optexity

PearSan Francisco, CA🇺🇸United StatesPosted 14 Aug 2026

Quick Overview

Work Type
Hybrid
Level
Mid Senior

Job Description

About Optexity

Optexity is a product-driven research lab building clinical reasoning and computer use models on data no other lab can reach. We deploy directly inside clinics and hospitals - including systems with no APIs, using integration infrastructure we've built and open-sourced - and in return become their preferred partner. That gives us proprietary clinical reasoning trajectories from practicing physicians, and a feedback loop between real patient encounters, our models, and the products built on top of them.

We're a small, fast-moving founding team with multiple published papers in NeurIPS, ICML, CVPR etc and background from Apple, Amazon, Microsoft, CMU, IIT.

We are backed by world-class investors and leaders like Jeff Dean, Neotribe VC, PearVC, Together Fund and Zapier Fund.

How we work
  • Customer obsession - we start with the customer and work backwards
  • Intellectual honesty - ideas matter more than titles; we communicate directly and assume good intent, even in disagreement
  • Bias for action - we build and learn with customers rather than debate in the abstract
  • Extreme ownership - we own outcomes, not just tasks, and see problems through

Why this role exists

Most research roles at this stage hand you a dataset everyone already has and ask you to be marginally better than the last person who tried. Here you get data nobody else has - real clinical reasoning trajectories from practicing physicians - and the room to figure out what to do with it. This is a founding research hire: you'll define the agenda as much as execute it, with direct founder access, real compute, and nothing between an idea and an experiment.

What you'll do
  • Work with real, proprietary clinical data from hospital and clinic partners to surface insights that shape model and product direction
  • Build clinical reasoning models that improve physician and clinic workflows
  • Design and publish benchmarks that expose where current LLMs fall short on real clinical reasoning
  • Evaluate computer-use models on real-world tasks
  • Own the training and evaluation pipeline end to end
  • Take open-ended problems from question to working model, with minimal predefined structure
  • Write up findings as technical reports and papers

Ideal candidate
  • Has real research experience - can define a problem, not just execute a known one
  • Has trained models before (not just fine-tuned APIs) and is fluent in Python
  • Master's or higher in ML or a related field
  • Energized by open-ended problems and ambiguity
  • Wants to publish, not just ship
  • Takes ownership without needing to be guided
  • Genuinely wants a startup over big tech - speed and ambiguity as defaults, not exceptions

Nice to have
  • Prior founder or founding-engineer experience
  • Strong product taste
  • Worked on healthcare datasets before
  • Built LLM-powered products before
  • Ambitions to start your own company someday - we'll support that path

What you get
  • Direct, daily work with the founders, plus exposure to board and investor conversations
  • Real ownership of technical direction, with scope that grows as the company does
  • Full compute and data to do the work properly
  • Competitive salary and meaningful equity
  • Visa sponsorship available

Skills

LLM
Python

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